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Updated: Jul 16, 2025

A Mass Spectrometry-Based Approach to Identify Phosphoprotein Phosphatases and their Interactors
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A Mass Spectrometry-Based Approach to Identify Phosphoprotein Phosphatases and their Interactors

Published on: April 29, 2022

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PP2A/B55α 酸酶抑制的分子机制由 IER5 抑制

Ruili Cao1, Daniel Td Jones1, Li Pan2

  • 1Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.

bioRxiv : the preprint server for biology
|September 11, 2023
PubMed
概括

这项研究揭示了IER5蛋白如何通过阻断基质结合来抑制PP2A/B55α酸酶活性. 这一发现澄清了PP2A/B55α调节的分子机制,并提出了新的治疗点.

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