影响COVID-19儿童简单发烧的因素:来自中国的病例对照研究
Haohao Wu1, Kang Du1, Xi Liang1
1Department of Neurology, Qujing First People's Hospital, Yunnan, Qujing, China.
Frontiers in neurology
|September 11, 2023
概括
儿童的COVID-19与老年儿童发生的简单发烧 (SFS) 有关. 发烧性的病史在COVID-19儿童中作为SFS的保护因素.
科学领域:
- 儿科 儿科 儿科
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 随着COVID-19的流行,在没有明确的解释的情况下,特别是在中国,简单的发烧 (SFS) 揭示了一种过年现象.
- 了解COVID-19儿童SFS的临床和辅助检查特征至关重要.
研究的目的:
- 分析COVID-19感染儿童中SFS的临床和辅助检查特征.
- 在儿科患者中调查COVID-19感染和SFS之间的关联.
主要方法:
- 一组78名患有SFS的儿科患者被分为COVID-19阳性 (病例) 和COVID-19阴性 (控制) 组.
- 分析了临床特征,辅助检查 (血液细胞计数,血清电解质) 和危险因素.
- 使用多变量逻辑回归来确定独立的风险和保护因素.
主要成果:
- 5岁以上的儿童在COVID-19阳性组 (47.4%) 的SFS比例明显高于对照组 (5%).
- 在COVID-19阳性组中观察到较低的白细胞,淋巴细胞和单细胞.
- 发烧发作史是一个独立的保护因素 (OR = 0.115,p = 0.009),而年龄则是COVID-19儿童SFS的独立风险因素 (OR = 1.042,p = 0.001).
结论:
- 患有SFS的COVID-19和没有COVID-19的儿童之间的年龄分布,性别,先前发烧史和低血量有所不同.
- 发烧发作史是儿童COVID-19病例中SFS的重要保护因素.
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