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一项研究评估维生素D对牙炎的抗炎作用:一个剂量依赖的随机对照试验
Rahul Srivastava1, Hadi Raza2, Pooja Kabra3
1Department of Oral Medicine and Radiology, Rama Dental College, Kanpur, Uttar Pradesh, India.
Journal of pharmacy & bioallied sciences
|September 11, 2023
概括
补充维生素D可以有效地减少牙炎. 降低牙炎症的最佳血液水平在30-35ng/ml之间,这表明维生素D与口腔健康之间存在显著联系.
科学领域:
- 口腔健康研究 口腔健康研究
- 营养科学 营养科学
- 炎症研究的研究.
背景情况:
- 维生素D缺乏与牙周炎风险增加有关.
- 较高的维生素D水平与减少炎症有关.
研究的目的:
- 研究维生素D补充剂对牙炎的影响.
- 确定最佳的维生素D水平,以减少牙炎症.
主要方法:
- 在451名参与者中进行了一项双盲,随机,受控试验.
- 参与者每天服用安慰剂,500 IU,1000 IU或2000 IU维生素D3三个月.
- 在整个研究过程中,对牙的分数和维生素D水平进行了监测.
主要成果:
- 维生素D补充剂显示,剂量依赖性减少了牙炎炎炎症.
- 在维生素D和牙指数得分之间观察到负相关性.
- 发现有效的抗炎维生素D血液水平在32-37ng/ml之间.
结论:
- 维生素D补充剂可以显著降低牙炎的严重程度.
- 血液中维生素D水平的最佳范围来对抗牙炎是30-35 ng/ml.
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