印度口腔癌人口查的成本效益:经济建模研究
Pooja Dwivedi1, Ayush Lohiya1, Pankaj Bahuguna2,3
1Department of Public Health, Health Technology Assessment, Kalyan Singh Super Specialty Cancer Institute, Lucknow, India.
The Lancet regional health. Southeast Asia
|September 11, 2023
概括
每10年进行一次的常规口腔检查 (COE) 是高风险的印度成年人最具成本效益的口腔癌查方法. 这种方法节省了成本,避免了大量的口腔癌死亡,改善了公共卫生结果.
科学领域:
- 卫生经济学 卫生经济学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 口腔癌查显著降低了死亡率.
- 评估查技术的成本效益对于公共卫生政策至关重要.
- 常见的方法包括传统的口腔检查 (COE),多胺蓝色染色 (TBS),口腔细胞学 (OC) 和基于光的检测 (LBD).
研究的目的:
- 在印度背景下评估不同口腔癌查技术的成本效益.
- 为了比较大规模查与高风险查策略.
- 确定最经济可行的方法来减少口腔癌的负担.
主要方法:
- 马尔科夫模型被用来模拟随时间推移的成本和健康结果.
- 使用了社会视角和3%的折扣率.
- 开发了两个模型:大规模查 (A模型) 和高风险查 (B模型) 与没有查.
- 概率灵敏度分析 (PSA) 解决了参数不确定性.
主要成果:
- 使用基于光的检测 (LBD) 进行的大规模查显示,事故病例最少,大多数死亡事件被避免.
- 高风险的查与常规口腔检查 (COE) 在10年间隔发生的最低终身成本.
- 发现高风险查策略,特别是10年后的COE,在每QALY的成本方面,在没有查方面占主导地位.
结论:
- 在印度,每隔10年进行常规口腔检查 (COE) 是在30岁以上高风险人群中进行口腔癌查的最节省成本的策略.
- 在高风险群体中进行有针对性的查提供了卓越的成本效益.
- 这些发现支持实施具有成本效益的查计划,以打击口腔癌.
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