研究听觉脑干引起的响应在不同的频率在亚临床甲状腺下腺体受试者的研究
Indira Jha1, Kabir Alam1, Kaushal K Keshari1
1Department of Physiology, IGIMS, Patna, Bihar, India.
Advanced biomedical research
|September 11, 2023
概括
亚临床甲状腺功能低下症可能导致中央听觉神经病变. 6KHz和80dB的听觉脑干唤起反应 (ABER) 测试可以在亚临床甲状腺功能低下症患者中早期检测到这一点.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 内分泌学 在内分泌学.
- 神经科学是一个神经科学.
背景情况:
- 在甲状腺功能下降的受试者中记录了听力恶化.
- 亚临床甲状腺功能低下症与延迟的听觉脑干唤起反应 (ABER) 波延迟相关.
- 之前的研究记录了亚临床甲状腺功能低下症患者在不同频率和分贝级别的ABER.
研究的目的:
- 用ABER来研究亚临床甲状腺功能低下症中的听觉通路功能.
- 为了确定ABER是否可以检测亚临床甲状腺功能低下患者的中枢神经病变.
主要方法:
- 进行了一项病例控制研究,对30名亚临床甲状腺功能低下患者和30名对照进行了研究.
- 排除标准包括各种疾病和可能影响听力或神经功能的药物.
- 听觉脑干唤起反应 (ABER) 在80dB和2,4和6KHz的频率进行.
主要成果:
- 与对照人群相比,亚临床甲状腺功能低下的受试者表现出延迟和显著的脑干唤起响应听力 (BERA) 波III,V和80dB的间峰延迟在测试频率 (2,4,6KHz) 上.
- 这些延迟表明潜在的中央听觉通路功能障碍.
结论:
- 特别是在6KHz和80dB的ABER测试,可以在亚临床甲状腺功能低下症患者中更早地检测到中枢神经病变.
- 这一发现强调了听力学评估在管理亚临床甲状腺功能低下症方面的重要性.
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