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重组因子IX Fc用于血友病B的大型手术:因子IX的血活性水平和有效的血静

Amy D Shapiro1, Hervé Chambost2, Margareth C Ozelo3

  • 1Indiana Hemophilia and Thrombosis Center, Indianapolis, Indiana, USA.

Research and practice in thrombosis and haemostasis
|September 11, 2023
PubMed
概括

延长半衰期的复合因子IX Fc融合蛋白 (rFIXFc) 在接受重大手术的血友病B患者中有效控制出血. 这种治疗可以达到足够的XIX因子水平,在高风险手术期间确保血液静止.

关键词:
第九因子XIX因子血友病 B 型 血友病 B 型血液静止 血液静止 血液静止再组合的融合蛋白质.手术 手术 手术 手术 手术 手术 手术

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