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Updated: Jul 16, 2025

Oral Health Assessment by Lay Personnel for Older Adults
Published on: February 2, 2020
痴呆症老年人中毒:系统范围审查和元分析
Ilsa R Wojt1, Edward C Y Lau1, Rose Cairns1,2
1The University of Sydney, School of Pharmacy, Faculty of Medicine and Health, Sydney, New South Wales, Australia.
痴呆症的老年人中毒很常见,通常涉及药物或家庭用品. 这些事件可能导致严重伤害,包括住院和死亡,突出需要更好的预防策略.
科学领域:
- 老年学是指老年学的学科.
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 患有痴呆症的老年人面临着中毒和相关不良结果的风险增加.
- 痴呆症显著增加了对意外或故意中毒的脆弱性.
研究的目的:
- 系统地审查和描述痴呆症患者中毒的主要病因,发病率,危险因素和患者结果.
- 综合现有的关于痴呆相关中毒的文献,以告知预防和干预工作.
主要方法:
- 在Medline,Embase,CINAHL和PsycINFO数据库 (2001-2021) 中进行了全面的文献搜索.
- 包括有关老年痴呆症 (包括阿尔茨海默病) 中毒的定量英语研究.
- 进行了一项元分析,以确定该人群中毒的发病率.
主要成果:
- 神经系统药物,特别是抗痴呆药物,二类药物和阿片类药物,涉及超过一半的药物中毒.
- 个人护理和家居用品是常见的非药物剂.
- 中毒发生率在3% (ICD定义) 到43% (药物不良事件定义) 之间.
- 风险因素包括多病症,精神药物使用和住院护理生活.
- 高达20%的中毒导致住院或死亡.
结论:
- 痴呆症患者中毒很常见,经常涉及常见药物或可获得的家庭物质.
- 与这些中毒相关的显著发病率和死亡率强调了需要进一步研究的需要.
- 加强公共卫生战略至关重要,以减轻痴呆症人口中可预防的伤害.
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