诺基诺的生态化学行为和生态环境影响
Li-Lian Wen1,2, Jin-Ming Song1,3,2,4, Xue-Gang Li1,3,2,4
1CAS Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, Shandong, China.
Ying yong sheng tai xue bao = The journal of applied ecology
|September 11, 2023
概括
合成诺基诺 (FQs),广泛使用的抗生素,在环境中作为伪持续性污染物持续存在. 它们的转变和迁移会影响生态系统,并促进抗生素耐药性.
科学领域:
- 环境化学环境化学
- 生态毒理学 生态毒理学
- 微生物学 微生物学
背景情况:
- 合成基诺 (FQs) 是重要的抗菌剂,在全球范围内排名第三.
- 过度使用和排放FQ对生态平衡,人类健康和可持续发展构成风险.
- 了解FQ生物地化学行为和环境影响对于负责任的管理至关重要.
研究的目的:
- 系统地审查合成基诺的生态化学行为和生态环境影响.
- 阐明FQs在体内和环境中的转化途径.
- 评估与FQ伪持久性相关的生态影响和风险.
主要方法:
- 关于FQ转化过程 (in vivo和环境) 的文献综述.
- 分析FQ迁移途径 (排泄,环境介质).
- 检查FQ转化机制 (吸附,光解,生物降解).
主要成果:
- FQs在体内发生有限的转化,大多数被排出不变或作为代谢物.
- 吸附,光解和生物降解等环境过程会改变FQ,但不会消除它们.
- 和其产品成为伪持久污染物,影响水生生物和促进抗菌素耐药性.
结论:
- FQ的迁移和转变导致伪持久性,带来重大生态风险.
- 环境FQ污染影响水生生物,生物地化学循环,并驱动抗菌素耐药性.
- 需要对FQ环境行为,生态风险和生物降解机制进行进一步的研究.
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