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血小板分布宽度和白细胞与心血管疾病有关:数据挖掘方法
Mohadeseh Poudineh1, Amin Mansoori2,3, Elias Sadooghi Rad4
1Student Research Committee, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Acta cardiologica
|September 11, 2023
概括
年龄,白细胞计数和血小板分布宽度是伊朗成年人心血管疾病 (CVD) 风险的关键指标. 这些血液学因素与心血管疾病的发展有显著的相关性,这凸显了它们在风险评估中的重要性.
科学领域:
- 心血管健康 心血管健康
- 血液学 血液学 血液学
- 流行病学 流行病学
背景情况:
- 心血管疾病 (CVD) 构成了全球健康的重大负担.
- 了解血液学因素与心血管疾病之间的关联对于风险分层至关重要.
研究的目的:
- 调查伊朗成年人队伍中各种血液学因素和心血管疾病 (CVD) 之间的关系.
- 确定心血管疾病发展的关键血液学预测因素.
主要方法:
- 一项前性研究,涉及9704名35-65岁的伊朗成年人.
- 数据收集包括人口特征和血液学因素.
- 使用后勤回归,决策树和启动森林分析来评估关联.
主要成果:
- 年龄,白细胞 (WBC) 计数和血小板分布宽度 (PDW) 与心血管疾病发展有很强的关联 (p<.001).
- 白血球 (OR: 1.22) 和年龄 (OR: 1.12) 被确定为显著的危险因素.
- 决策树和启动式森林模型强调年龄,WBC和PDW是最关键的因素,并指出性别和吸烟状况.
结论:
- 年龄,WBC和PDW被证实是影响心血管疾病发展的最关键因素.
- 这些发现强调了监测血液学参数对于该人群中心血管疾病风险评估的重要性.
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