同一个患者的精液参数在COVID-19诊断之前和之后的比较
Cihan Cakir1, Goktan Kuspinar1, Gizem Kurt1
1Department of Histology and Embryology, Uludag University School of Medicine, ART Center, Bursa, Turkey.
Journal of medical virology
|September 11, 2023
概括
严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 感染通过降低精液质量对男性生育能力产生负面影响. 在COVID-19期间的发烧进一步加剧了这些对精子参数的影响.
科学领域:
- 生殖医学 生殖医学
- 病毒学 病毒学
- 安德罗学与人类学
背景情况:
- 临床和组织病理学数据表明,冠状病毒病 (COVID-19) 对男性生殖系统的潜在负面影响.
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 是导致COVID-19的病毒.
研究的目的:
- 为了研究SARS-CoV-2感染对精液参数的影响.
- 为了比较同一患者COVID-19诊断前后的精液分析.
主要方法:
- 从医疗记录中对342个精液分析进行了回顾性分析.
- 包括COVID-19前后精液分析的患者 (n=114) 和年龄匹配的对照组 (n=114).
主要成果:
- 在SARS-CoV-2感染后观察到精液量,精子总数,渐进性运动性,总运动性和正常精子形态的显著下降.
- 在COVID-19期间的发烧对精液参数产生了负面影响,特别是精子度,与没有发烧的患者相比.
- COVID-19感染的持续时间 (短期与长期) 并没有显著改变精液参数的变化.
结论:
- SARS-CoV-2 感染与精液质量下降有关,可能会影响男性生育能力.
- 对精液参数的负面影响可能是持久的.
- 活跃的COVID-19感染期间的发烧是一个显著的危险因素,会对精子生成产生负面影响.
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