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对于常规的F-FDG uEXPLORER全身PET/CT扫描进行适当的协议
Huiran Hu1, Yanchao Huang1, Hongyan Sun2
1Nanfang PET Center, Nanfang Hospital, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou, 510515, Guangdong Province, People's Republic of China.
EJNMMI physics
|September 11, 2023
概括
与OSEM相比,HYPER代重建方法在全身PET/CT扫描上提供更优质的图像质量和病变检测. 这使得扫描协议的速度更快,最佳的诊断质量可以在1分钟内达到全剂量和2分钟的半剂量.
科学领域:
- 医疗成像医学成像
- 核医学就是核医学.
- 放射学 放射学是一门学科.
背景情况:
- 传统的PET扫描仪具有有限的轴视野 (AFOV),影响覆盖范围和检测效率.
- uEXPLORER全身PET/CT扫描仪具有194厘米的AFOV,显著提高了计数速度.
- 订制子集期望最大化 (OSEM) 是标准的,但需要早期代停止来管理噪音,可能会降低图像质量.
研究的目的:
- 评估HYPER代重建算法对病变可见性的影响,使用uEXPLORER全身PET/CT.
- 为了确定常规18F-FDG uEXPLORER全身PET/CT扫描的最佳扫描协议,使用全剂量和半注射剂量.
主要方法:
- 以OSEM和HYPER代算法重建的20个瘤患者扫描的回顾性审查.
- 在重建方法之间比较图像质量,噪音水平,SUVmax和瘤与背景比率 (TBR).
- 在不同的扫描时间 (1-5分钟) 和注射剂量 (全和半) 中评估图像质量.
主要成果:
- 通过HYPER的代重建,在1分钟 (全剂量) 和2分钟 (半剂量) 的时间内实现了出色的图像质量.
- OSEM需要2分钟 (全剂量) 和3分钟 (半剂量) 来获得类似的优质图像质量.
- HYPER代显示SUVmax和TBR显著更高,特别是在小病变中 (全剂量高达74.96%的SUVmax).
- 与OSEM相比,HYPER代的噪音水平较低.
结论:
- 最佳的临床方案是1分钟 (全剂量) 和2分钟 (半剂量) 的HYPER代重建.
- 对于OSEM来说,最佳方案是2分钟 (全剂量) 和3分钟 (半剂量).
- 为了准确量化小病变,优先使用HYPER代重建.
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