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Updated: Jul 16, 2025

A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice
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与功能性改变的NaV1.8通道相关的外周温度失调.

Simon Loose1, Annette Lischka2, Samuel Kuehs1

  • 1Department of Anesthesiology and Intensive Care & CBBM - Center of Brain, Behavior and Metabolism, University of Luebeck, Ratzeburger Allee 160, 23562, Luebeck, Germany.

Pflugers Archiv : European journal of physiology
|September 11, 2023
PubMed
概括

在电压关闭的通道NaV1.8中,一种罕见的SCN10A基因变异 (p.V1287I) 导致功能损失和功能增益. 这导致感觉神经元过度兴奋,解释了患者的温度调节失调和麻醉.

关键词:
道病变是一种通道病变.在 NaV1.8 中使用.在SCN10A中.感官神经病变是一种神经病变.通道中的.

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