结核病发病和治疗结果中的性别和性别差异
Djeneba Dabitao1, William R Bishai2
1Faculty of Pharmacy and Faculty of Medicine and Odonto-Stomatology, University Clinical Research Center (UCRC), University of Sciences, Techniques, and Technologies of Bamako (USTTB), Bamako, Mali.
Current topics in microbiology and immunology
|September 11, 2023
概括
男性比女性更容易患上活跃结核病,治疗结果也较差. 本综述探讨了导致结核病中这种性别偏见的生物和非生物因素.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 结核病 (TB) 不成比例地影响男性,与女性相比,活性肺结核病的发病率更高,治疗结果更差.
- 驱动这种观察到的结核病原和疾病进展中的性别偏差的潜在机制在很大程度上是未知的.
- 现有证据表明,生物 (例如,性激素,遗传) 和非生物 (例如,生活方式,医疗保健) 因素都可能导致结核病的性别差异.
结论:
- 需要进一步的研究,以阐明性别和性别在结核病原和治疗中的复杂相互作用.
- 了解这些基于性别的差异对于制定针对性结核病的预防和治疗策略至关重要.
- 未来的研究应该探索生物性别和与性别相关的因素之间的潜在交叉点,以充分解决结核病差异.
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