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Updated: Jul 16, 2025

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slan+单细胞杀死癌细胞,这些癌细胞被治疗性抗体所覆盖,这种抗体是由Trogoptosis造成的

Giulia Finotti1, Enrica Pietronigro1, Camillo Balanzin1

  • 1Section of General Pathology, Department of Medicine, University of Verona, Verona, Italy.

Cancer immunology research
|September 11, 2023
PubMed
概括

表达6-Sulfo LacNAc (slan) 的人类单细胞通过囊细胞分裂调解抗体依赖的细胞毒性 (ADCC),导致细胞死亡. 这些slan+单细胞还直接通过抗CD47抗体调解ADCC,这表明它们在癌症治疗中的作用.

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