预测毒和败血症休克手术患者的死亡率和不良事件的四种评估工具:一项比较研究
Yi-Chin Chu1, Yi Liu2, Shih-Feng Weng3
1MSN, RN, Department of Nursing, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Taiwan.
The journal of nursing research : JNR
|September 11, 2023
概括
修改后的PIRO (mPIRO) 评分有效预测了手术性败血症患者的死亡率和不良事件. 这种经过验证的工具具有高灵敏度和准确性,有助于临床决策.
科学领域:
- 败血症的研究研究.
- 临床评估工具 临床评估工具
- 手术患者的治疗结果.
背景情况:
- 手术患者的败血症死亡率很高 (约. 这是36%的百分比.
- 预易性,感染/损伤,反应,器官功能障碍 (PIRO) 评分被使用,但手术性败血症缺乏标准化.
- 需要一个更准确和标准化的评估工具来评估手术性败血症.
研究的目的:
- 开发一个修改的PIRO (mPIRO) 评分,不包括体温和包括血小板计数.
- 评估mPIRO在预测手术性败血症死亡率和不良事件中的敏感性和特异性.
- 为了比较mPIRO与SOFA,快速SOFA和PIRO的预测性能.
主要方法:
- 追溯观察队列研究.
- 对2055名患者记录的审查,其中103人符合手术性败血症的纳入标准.
- 统计分析以评估预测准确性 (灵敏度,特异性,AUC).
主要成果:
- mPIRO (≥4) 在死亡率预测方面表现出高灵敏度 (90.5%).
- 在不良事件预测方面,mPIRO显示出高灵敏度 (72%) 和特异性 (80%).
- mPIRO是死亡率最准确的预测指标 (AUC=0.83);SOFA (AUC=0.86) 和mPIRO (AUC=0.82) 是不良事件的顶级预测指标.
结论:
- mPIRO评分是一个有效,敏感和准确的工具,用于评估手术性败血症患者.
- mPIRO的易用性和强大的预测性能支持其临床应用.
- 建议mPIRO评分≥3作为潜在不良事件的指标.
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