循环症对前段结构和形眼睛形眼睛的硬膜厚度的影响
Ilayda Korkmaz1, Mine Esen Baris1, Suzan Guven Yilmaz1
1Department of Ophthalmology, Ege University Medical Faculty Hospital, Izmir, Turkey.
概括
局部循环酸盐化物诱导的循环明显减小了前硬膜厚度 (AST) 后面的硬膜刺激 (SS) 和深化前腔深度 (ACD). 这些变化凸显了循环的药物如何影响前段生物力学.
科学领域:
- 眼科医生 眼科 眼科
- 生物医学工程 生物医学工程
- 前段成像前段成像的使用
背景情况:
- 环性药物通常用于眼科,以暂时麻眼肌肉.
- 循环病对前段生物力学特性的影响,特别是膜,尚未完全理解.
- 前段光学连贯性断层扫描 (AS-OCT) 提供高分辨率成像,用于评估前段结构.
研究的目的:
- 为了研究局部环醇化物诱导的环病对前部细分的生物力学特征的影响.
- 使用AS-OCT量化前后循环之前和之后的中角膜厚度 (CCT),前腔深度 (ACD) 和前硬膜厚度 (AST) 的变化.
主要方法:
- 二十五名吸血志愿者进行了AS-OCT测量,测量了CCT,ACD和AST在关节 (SS) 周围的多个点.
- 在灌注局部环酸盐化物以诱导环症后,重复测量.
- 进行了统计分析,以比较循环前和循环后的测量.
主要成果:
- 在循环之后,观察到前腔深度 (ACD) 显著增加 (P=0.001).
- 在鼻腔和部象限 (P=0.00对所有) 中,在前面的皮厚度 (AST) 在后面的皮刺激 (AST-1和AST-2) 后显著稀薄.
- 在中角膜厚度 (CCT) 或在皮刺激水平 (AST-0) 上前膜厚度上没有发现显著的变化.
结论:
- 局部循环托拉酸化物诱导的循环 leads to显著的生物力学变化在前段的emmetropic眼睛.
- 观察到的缩组织在缩突起后部的稀薄和前腔室的深化表明体的放松或后部位移.
- 这些发现表明,循环的药物可以影响前段尺寸和膜生物力学,这可能是由于肌所施加的改变机械力.
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