在RanibiZumab-或AFLIBERCEPT-治疗的近视性冠状动脉新血管化中,的冠状动脉缩和视觉结果
Yu Kawashima1,2, Masayuki Hata1, Masahiro Miyake1
1Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Retina (Philadelphia, Pa.)
|September 11, 2023
概括
在基线时的斑点斑块缩预测了用抗VEGF疗法治疗的近视冠状腺新血管化 (mCNV) 的较差结果. 早期缩与更快的进展和较差的视觉预后有关.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 医疗治疗 医疗治疗
背景情况:
- 近视性冠状腺新血管化 (mCNV) 对视力构成重大威胁.
- 胆管缩,包括斑点缩 (PA) 和CNV相关的黄斑缩 (CNV-MA),可能会影响视觉结果.
- 了解缩的预测因素对于管理mCNV至关重要.
研究的目的:
- 用mCNV.在眼睛中识别斑点胆管缩症的预测因素.
- 评估缩在拉尼比祖马布或aflibercept治疗期间对视觉结果的影响.
- 要区分斑点性缩 (PA) 和与CNV相关的黄斑缩 (CNV-MA).
主要方法:
- 对82个未经治疗的mCNV眼睛进行了回顾性研究.
- 通过预先注射的拉尼比祖马布或阿弗利塞普特治疗.
- 在24个月内分析基线特征和视敏度变化.
主要成果:
- 九只眼睛 (11.0%) 具有基线黄斑PA.
- 患有PA的眼睛表现出较慢的视觉改善和更快的缩进展.
- 在PA组中,CNV-MA的发生频率更高 (P = 0.04).
- 在非PA眼中,较大的CNV和较薄的亚叶胆道厚度预测了CNV-MA,导致预后较差.
结论:
- 黄斑PA在基线是CNV-MA发展的重要风险因素.
- 基线PA与mCNV患者的视觉结果较差有关.
- 早期发现和监测PA对于管理mCNV至关重要.
更多相关视频
10:24Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
10.2K
10:14Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
3.2K
相关概念视频
Open Angle Glaucoma: Treatment
477
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
477
Angle Closure Glaucoma: Treatment
559
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
559
Glaucoma: Overview
618
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
618
