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相关概念视频

Feedback Regulation of Calcium Concentration01:27

Feedback Regulation of Calcium Concentration

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Calcium is an essential signaling molecule required for various cellular functions. Calcium pumps and ion channels on cell and organellar membranes, such as those on the endoplasmic reticulum (ER), regulate calcium concentrations inside the cell. They remain closed, keeping the cytosolic calcium levels low at a resting state.
Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...
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Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

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Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
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Calmodulin-dependent Signaling01:16

Calmodulin-dependent Signaling

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Calmodulin (CaM) is a calcium-binding protein in eukaryotes that controls various calcium-regulated cellular processes. It has four calcium-binding sites that bind calcium to form the calcium-calmodulin ( Ca2+-CaM) complex. GPCR stimulation increases the calcium levels in the cells that bind to CaM and induces a conformational change.
The Ca2+-CaM complex does not have enzymatic activity by itself. Instead, the complex binds downstream target proteins, including membrane proteins or enzymes,...
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Morphogenesis02:19

Morphogenesis

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Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
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Cell Motility through Blebbing01:16

Cell Motility through Blebbing

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Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
In multicellular...
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Hormones and Bone Tissue01:17

Hormones and Bone Tissue

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The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
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相关实验视频

Updated: Jul 16, 2025

Generation of Transgenic Hydra by Embryo Microinjection
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Generation of Transgenic Hydra by Embryo Microinjection

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在水的形态发生过程中普遍的波动.

Oded Agam1, Erez Braun2

  • 1The Racah Institute of Physics, Edmond J. Safra Campus, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.

Physical biology
|September 11, 2023
PubMed
概括

在水体再生过程中 (Ca2+) 的空间波动显示出普遍性质. 调节Ca2+活动与电场或乙醇可逆地停止再生,突出其在形态发生中的作用.

科学领域:

  • 发育生物学 发展生物学
  • 生物物理学的生物物理.
  • 细胞生物学 细胞生物学

背景情况:

  • 动物发育中的形态过渡是由集体物理过程驱动的.
  • (Ca2+) 是一个关键的信号分子,参与形态发生.
  • 了解Ca2+在再生中的作用对于发育生物学至关重要.

研究的目的:

  • 描述Ca2+在*Hydra*再生过程中的空间波动的普遍性质.
  • 研究外部电场和间隙结阻对Ca2+活动和再生的影响.
  • 开发一个理论模型来解释观察到的Ca2+动态.

主要方法:

  • 使用外部电场和乙醇对Ca2+活动进行实验性操纵.
  • 对Ca2+空间波动及其统计特征的定量分析.
  • 基于倾斜的双井潜力的场理论模型的开发.

主要成果:

  • 在*Hydra*再生过程中的Ca2+空间波动表现出普遍的特征.
  • 外部电场增强了Ca2+活动和空间相关性,而肝醇则抑制了它们.
  • 2+波动的统计性质显示出普遍分布,并且该组织运行时接近可比稳定.
关键词:
水的再生是水的再生.稳定性比稳定性比稳定性形态发生 (morphogenesis) 是一种形态的产生.全球的波动

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Generation and Long-term Maintenance of Nerve-free Hydra
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Generation and Long-term Maintenance of Nerve-free Hydra

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Fluorescent Calcium Imaging and Subsequent In Situ Hybridization for Neuronal Precursor Characterization in Xenopus laevis

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相关实验视频

Last Updated: Jul 16, 2025

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Generation of Transgenic Hydra by Embryo Microinjection

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Generation and Long-term Maintenance of Nerve-free Hydra
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Generation and Long-term Maintenance of Nerve-free Hydra

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Fluorescent Calcium Imaging and Subsequent In Situ Hybridization for Neuronal Precursor Characterization in Xenopus laevis
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Fluorescent Calcium Imaging and Subsequent In Situ Hybridization for Neuronal Precursor Characterization in Xenopus laevis

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结论:

  • 2+场在水体的形态发生和再生中起着突出的作用.
  • Ca2+活动是局部局部的,Hydra*组织在双稳定性开始时运行.
  • 这些发现提供了关于发展过程中强大的形态转换机制的见解.