慢性肺炎和多病症:识别和解决综合性发生
Leonardo M Fabbri1, Bartolome R Celli2, Alvar Agustí3
1Section of Respiratory Medicine, Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
The Lancet. Respiratory medicine
|September 11, 2023
概括
大多数患有慢性阻塞性肺病 (COPD) 的患者也患有其他慢性疾病,经常死于非呼吸系统疾病. 将COPD视为多病症状态或综合症的一部分,可以改善诊断和以患者为中心的护理.
科学领域:
- 肺部医学 肺部医学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 大多数患有慢性阻塞性肺病 (COPD) 的患者经历多种慢性疾病.
- 虽然严重的COPD可能导致呼吸衰竭,但大多数COPD患者的死亡是由于心血管疾病和癌症等非呼吸系统疾病造成的.
- 老龄化,吸烟和污染等共同的风险因素有助于这些疾病的同时发生.
研究的目的:
- 提出了解COPD的范式转变,从单一的疾病与并发症转变为多病症状态.
- 引入综合症的概念来解释COPD患者疾病的聚类.
- 突出COPD管理中的综合学方法的临床影响.
主要方法:
- 关于COPD和多病症现有文献的概念分析和综合.
- 将综合症框架应用于COPD的背景.
- 讨论诊断和管理的潜在临床应用.
主要成果:
- 慢性肺炎患者经常出现多种同时发生的慢性疾病.
- 非呼吸系统疾病,特别是心血管疾病和癌症,是COPD死亡的主要原因.
- 综合症学的观点为COPD病态的聚类提供了一个新的解释.
结论:
- 需要一种综合学方法,将COPD视为具有共享机制的多病态状态的一部分.
- 这种方法可以推进COPD的预防,诊断和管理策略.
- 综合,以患者为中心的护理对于解决COPD患者复杂的健康需求至关重要.
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