用四维自动化左心房量化心声扫描评估左心房形态和功能的变化,用于冠状动脉慢流现象和保存左心室射出分数的患者
Yumeng Xing1, Yinjia Zhang1, Rui Zhao2
1Department of Ultrasound, Huadong Hospital, Fudan University, 221 West Yanan Road, Shanghai 200040, China.
International journal of cardiology
|September 11, 2023
概括
冠状动脉缓慢流现象 (CSFP) 与左心房功能受损有关,特别是储功能受减少的LA应变 (LASr) 和总排空分数 (LATEF) 指示. 在CSFP患者中,LASr可以预测左心室填充压力升高的情况.
科学领域:
- 心脏病学 心脏病学
- 心脏成像 - - 心脏成像
- 左心房的功能功能 左心房功能
背景情况:
- 冠状动脉缓慢流现象 (CSFP) 与左心室扩张功能障碍 (LVDD) 有关.
- 左心房 (LA) 应变是评估LVDD的一个关键指标.
- 四维自动化LA量化 (4D自动LAQ) 提供了先进的LA分析.
研究的目的:
- 用4D自动LAQ在CSFP患者中评估LA形态和功能的亚临床变化.
- 评估4D自动LAQ在识别CSFP中的LA功能障碍方面的实用性.
- 为了将LA功能参数与CSFP严重程度和特征相关联.
主要方法:
- 48名CSFP患者和46名对照患者在心肌梗塞框架计数 (TFC) 中接受了冠状动脉血管学和血栓分析.
- 4D自动LAQ被用于量化LA体积,纵向和周围应变 (水库,管道,收缩阶段) 和排空分数 (LATEF,LAAEF,LAPEF).
主要成果:
- 与对照组相比,CSFP患者的LA纵向储应变 (LASr),导管应变 (LAScd),收缩应变 (LASct),导管周围应变 (LAScd-c),LATEF和LAPEF显著降低.
- LASr和LATEF独立地与CSFP相关.
- LASr在区分CSFP与对照的过程中表现出高灵敏度和特异性,并预测LV填充压力升高.
结论:
- 在CSFP患者中,LA储功能受损,反映在LASr和LATEF的减少中,显而易见.
- LASr是CSFP中LV填充压力升高的有价值的预测指标.
- 在检测单血管CSFP中的LA储存器功能障碍方面,LASr比LATEF更敏感,LAD参与具有更大的影响.
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