为所有患者进行门节约性大动脉根置换?
Tristan Ehrlich1, Karen B Abeln1, Lennart Froede1
1Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg/Saar, Germany.
The Journal of thoracic and cardiovascular surgery
|September 11, 2023
概括
节能根置换 (VSRR) 提供了良好的结果,但随着61岁以上的年龄和并发症的增加,生存率下降. 与门相关的无并发症生存率在各个年龄段仍然有利.
科学领域:
- 心血管外科心血管外科
- 大动脉门外科手术
- 大动脉根的替代术
背景情况:
- 节能根置换 (VSRR) 与有利的生存率和较低的关相关并发症 (VRCs) 有关.
- 患者并发症和年龄对VSRR结果的影响需要进一步调查.
研究的目的:
- 分析VSRR后的生存率和VRC的频率.
- 评估患者并发症和年龄对VSRR结局的影响.
主要方法:
- 一组1156名患者在1995年至2021年期间接受双或三大动脉的VSRR治疗.
- 基于患者的并发症和手术时的年龄,对生存率和VRCs的分析,并使用ROC分析来确定年龄截止.
- 平均随访时间为6.7年,完成率为95%.
主要成果:
- 平均15年生存率为74.7%. 死亡的患者年龄较大,并患有更多的并发病 (例如冠状动脉疾病).
- 61岁以上的年龄是死亡率的唯一显著预测因素 (P < .001).
- 15年生存率为87.1%的患者<61年对比55.3%的患者>61年. 在15年内,无VRC存活率为66.8%,年轻患者的比率更高.
结论:
- 在VRCs的低发病率下,VSRR表现出极好的耐用性.
- 患者年龄>61岁和并发症,特别是冠状动脉疾病,与生存率下降有关.
- 尽管与年龄相关的生存差异,VSRR提供良好的免于门相关的并发症.
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