使用电子健康记录数据挖掘用于心力衰竭的亚型
Matti A Vuori1,2,3, Tuomo Kiiskinen4, Niina Pitkänen5
1Division of Medicine, University of Turku, Kiinamyllynkatu 10, Turku, FI-20520, Finland. makvuo@utu.fi.
BMC research notes
|September 12, 2023
概括
电子健康记录 (EHR) 数据挖掘使用喷射分数 (EF) 和实验室数据准确地分类心力衰竭 (HF). 这种方法改善了HF的分类,特别是对于具有减少EF (HFrEF) 的HF.
科学领域:
- 心脏病学 心脏病学
- 医疗信息学 医疗信息学
- 数据科学数据科学数据科学
背景情况:
- 准确的心力衰竭 (HF) 亚型化对于有效的治疗和预后至关重要.
- 基于注册表的高频子类型传统上依赖于结构化数据,可能缺少细微信息.
- 电子健康记录 (EHR) 数据提供了丰富的非结构化临床信息来源.
研究的目的:
- 评估EHR数据的文本挖掘的有效性,以改善基于注册表的心力衰竭 (HF) 亚型化.
- 为了评估算法衍生的射出分数 (EF) 在分类HF亚型时的准确性.
- 为了比较基于传统HF诊断的生存分析与基于算法的亚型化.
主要方法:
- 从43,405个人的非结构化EHR数据中进行文本挖掘,以识别弹射率 (EF) 的提及.
- 算法识别的EF与200名随机选择的患者的临床评估的验证.
- 整合结构化实验室数据用于HF亚型,分为HF轻度减少EF (HFmrEF),HF保存EF (HFpEF) 和HF减少EF (HFrEF).
主要成果:
- 该算法在86%的案例中正确将EF分配到适当的高频子类型范围.
- 对HFrEF和HFmrEF观察到高灵敏度,特异性,正预测值 (PPV) 和负预测值 (NPV).
- 死亡风险从HFmrEF逐渐增加到HFpEF到HFrEF,与传统诊断一致.
结论:
- 定量喷射分数 (EF) 数据可以使用文本挖掘有效地从电子健康记录中提取.
- 电子健康记录数据与实验室数据相结合,可以实现相当准确的高频子类型,特别是对于HFrEF.
- 开发的方法显示了提高HF分类和流行病学研究的潜力.
关键词:
数据挖掘是一种数据挖掘.喷射分数的喷射分数是什么电子健康记录电子健康记录在HFmrEFEF中使用.HFpEF HFpEF 的意思是什么这就是HFrEFEF.心脏衰竭是因为心脏衰竭.文本挖掘 (Text Mining) 是一种文字挖掘方式.更多相关视频
05:15Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
107
09:20Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications
Published on: February 23, 2019
8.7K
相关概念视频
01:30Heart Failure IV: Classification and Diagnostic Evaluation
19
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
19
01:30Heart Failure VII: Nursing Interventions
90
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
90
01:22Heart Failure VI: Adjunct Therapies
16
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
16
01:30Heart Failure V: Medical Management
12
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
12
01:17Pathophysiology of Heart Failure
1.6K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.6K
01:22Heart Failure Drugs: β-Blockers
363
β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation,...
363