感冒对中风入院的额外影响:对缺血性和出血性中风的不同影响
Peilin Liu1, Zhuangzhuang Chen1, Suqin Han2,3
1Department of Neurology, The Second Hospital of Tianjin Medical University, Tianjin, China.
概括
感冒症状显著增加了中风的入院率,缺血性中风的影响滞后,持续时间比直接,短暂的对脑内出血的影响更长. 公共卫生干预措施至关重要.
科学领域:
- 环境流行病学环境流行病学
- 心血管健康的心血管健康
- 气象对健康的影响
背景情况:
- 流行病学研究表明,低环境温度与中风风险增加之间存在联系.
- 现有的数据有限,特别是关于与特定中风亚型的关联.
研究的目的:
- 量化感冒和中风病例之间的关系.
- 为了区分感冒对缺血性中风和脑内出血 (ICH) 的影响.
主要方法:
- 分析了天津144405例中风病例 (2016-2020年),并使用了气象数据.
- 利用了通用增值模型与分布式滞后非线性模型来评估寒冷时期的影响.
- 研究了12个基于温度值和持续时间的冷势定义,控制温度的滞后和非线性影响.
主要成果:
- 感冒与中风病例的显著增加有关.
- 风险随着温度值的降低而增加,但寒冷周期的持续时间没有显著影响.
- 缺血性中风患者的入院显示了对感冒的延迟,长时间的反应 (峰值RR 1.05在13d的滞后),而ICH患者的入院具有立即的,短期的影响 (峰值RR 1.17在0d的滞后).
- 大约14.15%的中风病例归因于寒冷时期,ICH显示较高的负担,除非在严格的温度定义下.
结论:
- 感冒增加了中风风险,缺血性中风 (延迟,持续时间较长) 和ICH (立即,持续时间较短) 的时间模式不同.
- 这些发现支持开发中风的寒冷时期早期预警系统.
- 强调需要进行公共卫生干预,以减轻与感冒相关的不良健康结果.
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