移植脏接受者的移植淋巴瘤:一个病例报告
Ji Hyun Yeom1,2, Won Kim1,2,3, Kyung Pyo Kang1,2,3
1Department of Internal Medicine, Jeonbuk National University Hospital, Jeonju, Korea.
Korean journal of transplantation
|September 12, 2023
概括
移植后的淋巴增殖性疾病 (PTLD) 可以模仿移植后的感染. 这一案例突出了EBV阳性淋巴瘤的发烧和移植问题,强调了差异诊断中的PTLD.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 在瘤学瘤学.
- 病毒学 病毒学
背景情况:
- 移植后淋巴增殖性疾病 (PTLD) 是固体器官移植后的严重并发症.
- PTLDs的特点是淋巴细胞的异常增殖,并且与爱斯坦-巴尔病毒 (EBV) 感染密切相关.
研究的目的:
- 报告艾普斯坦-巴尔病毒阳性扩散型大B细胞淋巴瘤的病例,该淋巴瘤在移植接受者身上呈现为并发症.
- 突出考虑PTLD在发烧性移植患者与移植相关症状的差异诊断中的重要性.
主要方法:
- 一个37岁的女性脏移植接受者的病例报告,发烧和移植不适.
- 诊断工作包括实验室检测,增强的腹腔皮层计算机断层扫描,并最终进行移植切除术.
- 对脏的组织病理学检查证实了EBV阳性扩散型大B细胞淋巴瘤.
主要成果:
- 患者出现了发烧,移植不适和血流,最初因尿路感染和移植不耐症综合征而接受治疗.
- 尽管接受了治疗,但症状恶化,需要移植切除术.
- 组织学证实爱斯坦-巴尔病毒阳性扩散型大B细胞淋巴瘤是病人的病因.
结论:
- PTLD可以表现出模仿常见并发症的非特异性症状,例如尿路感染或移植患者的移植不耐症综合征.
- 在差异诊断中早期考虑PTLD对于及时和适当的管理至关重要.
- 这个案例强调了EBV和PTLD在移植的背景下之间的关联.
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