相关实验视频

Updated: Jul 16, 2025

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
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Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

Published on: July 8, 2025

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在CASP15中使用ClusPro LigTBM服务器进行精确的联结蛋白对接.

Sergei Kotelnikov1,2, Ryota Ashizawa1,2, Konstantin I Popov3

  • 1Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York, USA.

Proteins
|September 12, 2023
PubMed
概括

基于模板的配体对接,像ClusPro ligTBM一样,在CASP15竞赛中被证明是非常有效的,用于预测小分子与蛋白质标的结合. 这种利用同质性的方法,在AlphaFold2模型上表现优于直接对接.

关键词:
在AlphaFold2模型中.布里卡德宏观周期建模在ClusPro的对接程序中.在 FTMap 蛋白质映射中.基于模板的连接器对接.

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