巴基斯坦人口中非活化COVID-19疫苗的短期副作用:基于调查的跨部门研究
Zunaira Nawaz1, Mariyam Zahid2, Mariam Sajjad2
1Department of Medical Unit I, Civil Hospital, Dow University of Health Sciences, Karachi, Pakistan.
JPMA. The Journal of the Pakistan Medical Association
|September 12, 2023
概括
评估了非活化冠状病毒疾病-2019疫苗的短期副作用. 年轻女性在接种Sinopharm或CoronaVac疫苗后报告了更多轻微症状,例如注射部位疼痛.
科学领域:
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 全球推出2019年冠状病毒病 (COVID-19) 疫苗对于控制大流行病至关重要.
- 失活的疫苗,如Sinopharm和CoronaVac,占全球疫苗管理的很大一部分.
- 了解这些疫苗的短期不良影响和相关的人口因素对于公众的信心和疫苗安全监测至关重要.
研究的目的:
- 为了评估两种无活化COVID-19疫苗:Sinopharm和CoronaVac.后的短期不良影响的发生率.
- 确定与这些疫苗副作用的发生相关的人口因素,包括年龄和性别.
主要方法:
- 在2021年8月至10月期间,在巴基斯坦卡拉奇进行了一项横截面研究.
- 通过在线和印刷调查,从896名接受过至少一剂新药或CoronaVac疫苗的成年参与者收集了数据.
- 使用SPSS 22进行了统计分析,以确定副作用的发生率和相关的人口因素.
主要成果:
- 副作用的总发病率为Sinopharm的第一剂后63.3%,第二剂后55.2%,CoronaVac的第一剂后65.4%,第二剂后61.4%.
- 女性性别和年龄较小 (18-30岁) 与报告副作用的风险较高显著相关 (p<0.05).
- 大多数报告的症状都是轻微的,主要是注射部位疼痛.
结论:
- 失活的COVID-19疫苗,Sinopharm和CoronaVac,与短期的高发病率有关,通常是轻微的不良反应.
- 年轻人和女性更有可能报告这些症状,特别是注射部位疼痛.
- 这些发现有助于对COVID-19疫苗的持续安全监测,并突出了潜在副作用报告的人口因素.
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