门说明书表面图案对门水力动力学性能的影响
Aili Wang1, Yumiao Wang1, Wanbing Liu2
1State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China.
The International journal of artificial organs
|September 12, 2023
概括
在人工心脏门传单上用平行槽图案改变烧解碳微结构会影响水力动力性能,影响平均压力梯度,有效孔面积和反分数.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 心血管研究研究心血管研究
背景情况:
- 人工心脏门对于治疗心脏膜疾病至关重要.
- 氧化碳微结构影响了机械心脏门的性能.
- 了解这些影响是改善门设计和患者治疗结果的关键.
研究的目的:
- 为了研究人工心脏门小册子上的 pyrolytic 碳的微结构如何影响它们的水力动力学性能.
- 评估激光雕刻的平行槽图案对关键血液动力学参数的影响.
主要方法:
- Bileaflet 机械 (GKS 23 和 29 A) 根据 ISO5840.0 标准进行了测试.
- 测量了血液动力学参数,包括平均压力梯度 (MPG),排泄率 (RF) 和有效孔径面积 (EOA).
- 通过激光蚀刻在传单表面创建了一个平行槽图案,并重新测试了门.
主要成果:
- 平行槽模式改变了MPG,EOA和RF.
- 一般来说,MPG在模拟后会增加.
- EOA显示出不同的反应 (在23A中较大,在29A中较小),RF显示出反向关系.
- 射频在5 L/min (45 bpm) 降低,但在7 L/min (70 bpm) 显示复杂的变化.
结论:
- 热溶性碳片的表面微结构显著影响人工心脏门的水力动力性能.
- 平行槽模式提供了一种调节门血液动力学的方法,尽管效果因门大小和流量条件而异.
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