在紧急输血中对O阳性血液的质量改善审查
Rakin Chowdhury1, Bronwyn A Williams2, Sue Williams2
1Princess Alexandra Hospital, Pathology Queensland, Brisbane, Australia.
Transfusion
|September 12, 2023
概括
在特定患者群体的紧急输血中使用O阳性红细胞可以节省O阴性单位,而不会影响患者的结果. 需要进一步的前性研究来优化O阳性血液的使用,并了解免疫率.
科学领域:
- 输血医学 输血医学
- 免疫学 免疫学 免疫学
背景情况:
- 实施了一项新的政策,用于在成年男性和绝经后女性的紧急输血中使用O阳性红细胞.
- 本研究评估了这一政策对输血实践和免疫率的影响.
研究的目的:
- 评估O阳性血液使用引入后紧急红细胞输血实践的变化.
- 为了确定与O阳性血液在紧急情况下的使用相关的红细胞合免疫率.
主要方法:
- 从2020年6月到2021年6月,全州对紧急输血进行了回顾性审查.
- 从实验室系统和医疗记录中收集了患者人口统计数据,输血指示,血液单位使用 (O 阳性与O 阴性) 和共免疫.
主要成果:
- 超过2354个红细胞单位被输血给了1013名患者. 0阳性单位占紧急输血的46.9%,节省了1103个O阴性单位.
- 尽管有政策,但30.8%的O阴性单位在没有强制性指示的情况下被输血.
- 红细胞配免疫发生在4.3%的输血后患者中,抗E和抗D是最常见的抗体.
结论:
- 使用O阳性血液进行紧急输血的政策成功地保存了O阴性单位,没有对患者产生不良后果.
- 有机会进一步优化O阳性血液在紧急输血中的利用.
- 建议进行前性研究,以更好地了解这种情况下的红细胞合免疫率.
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