纤维肌痛患者的心血管风险因素和事件
Fabiola Atzeni1, Mariateresa Cirillo1, Valeria D'Amico1
1Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
The Israel Medical Association journal : IMAJ
|September 12, 2023
概括
与一般人群相比,纤维肌痛患者患心血管疾病的风险更高,包括高血压和糖尿病. 这表明一种特定的风险因素概况有助于增加纤维肌痛心血管负担.
科学领域:
- 心血管健康 心血管健康
- 类风湿病学 类风湿病学
- 流行病学 流行病学
背景情况:
- 纤维肌痛与神经内分泌,炎症和凝血异常有关.
- 这些特征可能有助于心血管疾病的发展.
- 纤维肌痛的精确心血管风险概况需要进一步定义.
研究的目的:
- 将女性纤维肌痛门诊患者的心血管风险因素和事件与意大利普通人口进行比较.
主要方法:
- 利用CUORE项目的标准来评估心血管风险因素和事件.
- 包括62名女性纤维肌痛患者和4093名女性对照 (年龄35-75岁).
主要成果:
- 纤维肌痛患者的高血压,糖尿病,心房动和过渡性缺血性发作的患病率显著增加.
- 心血管总负担在纤维肌痛女性中显著更高.
- 在禁食葡萄糖,脂质样本,BMI或代谢综合征 (MetS) 中没有发现显著差异.
- 方法限制可能低估了MetS率.
结论:
- 纤维肌痛与更大的心血管负担有关.
- 这种增加的负担可能是由纤维肌痛的独特风险因素组成的.
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