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在移植中的皮质类固醇剂量及其对手术并发症的影响:系统性审查
Nasser Simforoosh1, Amirhossein Nayebzade, Mehdi Dadpour
1>From the Shahid Labbafinejad Medical Center, Center of Excellence in Urology, Urology and Nephrology Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran.
概括
在移植后减少皮质类固醇剂量可能会降低手术并发症风险. 医疗保健提供者应根据患者个体需求量身定制类固醇治疗,以获得最佳的结果.
科学领域:
- 科和移植手术 移植手术
- 药理学和治疗学 药理学和治疗学
背景情况:
- 皮质类固醇通常用于移植后,但它们与手术并发症的关联需要进一步调查.
- 现有的文献还没有系统地审查皮质类固醇剂量对移植后手术并发症的影响.
研究的目的:
- 系统地调查皮质类固醇使用与移植接受者手术并发症发生率之间的相关性.
主要方法:
- 在PubMed和Embase数据库中进行了系统的文献搜索,直到2023年4月.
- 包括的研究是回顾性和前性队列,研究移植患者的皮质类固醇和手术并发症之间的关联.
- 搜索词包括"脏移植"",类固醇"和"并发症".
主要成果:
- 系统性审查包括了8项涉及3274篇文章的研究.
- 结果表明,较低的术后皮质类固醇剂量与手术并发症发生率降低有关.
- 研究包括回顾性和前性队列,患者平均年龄为42.1岁.
结论:
- 降低移植后的皮质类固醇剂量可能会降低手术并发症率.
- 这种策略似乎是可行的,以尽量减少脏移植患者的手术风险.
- 医疗保健提供者的个性化评估对于确定最佳皮质类固醇剂量和持续时间至关重要.
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