在日本,喘控制状态与与健康相关的生活质量之间的关系:一个跨部分混合方法研究
Hiroyuki Nagase1, Risako Ito2, Moe Ishii3
1Division of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo, 173-8605, Japan. nagaseh@med.teikyo-u.ac.jp.
Advances in therapy
|September 12, 2023
概括
控制喘在日本显著影响生活质量和工作生产力. 即使在药物治疗下,如果喘不能得到良好的控制,也会导致更大的症状负担和减少日常功能.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 生活质量研究 研究 生命质量研究
- 医疗保健服务研究 医疗服务研究
背景情况:
- 在日本,人们对喘多维影响的理解有限.
- 需要对喘负担进行系统的定性研究.
研究的目的:
- 调查日本的喘控制,HRQoL,工作生产力和症状负担.
- 探索失控喘对患者生活的质量影响.
主要方法:
- 在ICS/LABA上对患有喘的日本成年人进行横截面混合方法研究.
- 使用AHQ-33,J-LCQ和WPAI:喘进行定量评估.
- 定性采访,以探索HRQoL对非控制性喘的影响.
主要成果:
- 45.2%的患者患有未得到良好控制 (NWC) 的喘.
- 北北中心喘患者报告HRQoL更差,咳负担更高,工作/活动障碍更大.
- 在喘控制,咳和HRQoL之间发现了显著的相关性.
结论:
- 尽管坚持ICS/LABA,但NWC喘显著增加了症状负担,并减少了HRQoL.
- 咳负担是与HRQoL相关的关键因素,这表明它在治疗策略中的重要性.
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