背部和腹部前-桃体网络是年龄相关认知衰退中风险决策的基础
Ping Ren1, Manxiu Ma2, Yuchuan Zhuang3
1Department of Geriatric Psychiatry, Shenzhen Mental Health Center/Shenzhen Kangning Hospital, Shenzhen, Guangdong, China. pingren1982@hotmail.com.
GeroScience
|September 12, 2023
概括
认知能力下降会影响老年人的风险决策. 大脑成像揭示了背部和腹部前额桃体通路的不同作用,特别是在认知障碍患者中,影响金融剥削风险.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 老年学是指老年学的学科.
背景情况:
- 老年人在不确定性下面面临决策的挑战,增加了金融剥削的风险.
- 认知衰退对风险决策及其神经基础的影响需要进一步研究.
研究的目的:
- 研究认知完整性如何影响老年人的冒险行为.
- 探索背部和腹部前-桃体连接在与年龄相关的决策中的可分离的角色.
主要方法:
- 使用爱荷华州博任务与36名年轻人和51名老年人.
- 员工休息状态和与任务相关的功能磁共振成像 (fMRI).
- 与认知状态和冒险行为相关的大脑连接.
主要成果:
- 与年轻人相比,在老年人中观察到显著的行为和前额桃体网络变化.
- 与年龄相关的风险承担的影响在认知正常和受损的老年人之间有所不同.
- 在认知障碍的老年人中发现了腹部前额-杏仁核连接和任务表现之间的正相关性.
- 在认知障碍的老年人中,确定了背部前额-杏仁核连接和任务表现之间的负相关性.
结论:
- 额头-桃体网络对于理解衰老中风险决策的改变至关重要.
- 背部和腹部前-桃体通路在决策中起着不同的作用,特别是在认知衰退时.
- 研究结果表明,在认知障碍的老年人中,存在潜在的金融剥削风险的特定神经机制.
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