比较两种放松程序以缓解多发性硬化症的疲劳:单盲随机对照试验
Guadalupe Garis1,2, Christian Dettmers3, Andrea Hildebrandt4
1Department of Psychology, Carl Von Ossietzky University Oldenburg, Oldenburg, Germany. g.garis1992@gmail.com.
概括
渐进性肌肉放松 (PMR) 在多发性硬化症 (MS) 患者中显著降低了疲劳. 深呼吸 (DB) 和PMR改变了自主神经系统 (ANS) 活动,但只有PMR减轻了疲劳.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 心理生理学 心理生理学
背景情况:
- 疲劳是多发性硬化症 (MS) 的常见和使人虚弱的症状.
- 有各种放松技术,但它们对MS疲劳和自主神经系统 (ANS) 活动的比较有效性尚不清楚.
- 研究了生物反支持的放松练习,特别是深呼吸 (DB) 和渐进性肌肉放松 (PMR).
研究的目的:
- 为了比较DB和PMR对MS患者减轻疲劳的影响.
- 评估这些放松技术对ANS活动的影响.
- 为了评估疲劳诱导警任务与心率变化 (HRV) 测量相结合的实用性.
主要方法:
- 一个单盲随机临床试验,涉及34名多发性硬化症患者.
- 使用HRV对DB的响应来评估心血管完整性.
- 管理一个警任务,其次是DB或PMR,在基线,任务后和干预后进行疲劳和HRV测量.
主要成果:
- 只有PMR导致了短期疲劳的显著减少.
- 无论是DB还是PMR都影响了ANS的活动.
- 警任务增加了疲劳,降低了副交感HRV;特征疲劳与HRV有负相关性.
结论:
- 在患有MS的个体中,PMR有效缓解短期疲劳.
- 警任务和HRV测量范式可以帮助评估减少疲劳的干预措施.
- 未来的研究应该探索更长,更频繁的放松课程,特别是对于轻度到中度疲劳的人来说.
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