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Updated: Jul 16, 2025

Application of CRISPR Interference CRISPRi for Gene Silencing in Pathogenic Species of Leptospira
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工程结合式CRISPR-Cas9系统用于针对性控制肠道病原体和抗生素耐药性

Haiqing Sheng1,2, Sarah Wu2, Yansong Xue1

  • 1Animal, Veterinary and Food Science, University of Idaho, Moscow, Idaho, United States of America.

PloS one
|September 12, 2023
PubMed
概括

通过结合性等离子体传递的CRISPR-Cas9技术有效向并消除诸如大肠杆菌和沙门氏菌等致病细菌. 这种方法有望降低抗生素耐药性,并防止肠道感染,而不损害有益的肠道微生物.

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