在帕金森病中深静脉血栓的发生率
Emine Afsin1, Zeliha Coşgun2, Ramazan Kurul3
1Department of Chest Diseases, Bolu Abant Izzet Baysal Unıversıty, Bolu, Turkey.
Neurological research
|September 12, 2023
概括
深静脉血栓 (DVT) 在没有已知的危险因素的帕金森病 (PD) 患者中很少见. 然而,在晚期PD阶段,对DVT的警至关重要,特别是在使用辅助设备和恶化呼吸障碍时.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 血管医学 血管医学
背景情况:
- 静脉血栓栓塞 (VTE) 是帕金森病 (PD) 死亡的一个重要原因.
- 关于PD与深静脉血栓瘤 (DVT) 之间的特定关联的研究有限.
研究的目的:
- 在帕金森病患者中前性地确定DVT的频率.
- 为了确定PD进展标志物和DVT风险之间的潜在相关性.
主要方法:
- 对37名PD患者的前性评估,没有先前存在的DVT风险因素.
- 数据收集包括人口统计,疾病持续时间,Hoehn-Yahr (H-Y) 阶段,SpO2,心率,辅助设备使用,人体测量和mMRC呼吸障碍得分.
- 下肢多普勒静脉超声波用于查DVT.
主要成果:
- 深静脉血栓症 (DVT) 仅在一个患者 (2.7%) 检测到.
- 在Hoehn-Yahr (H-Y) 阶段和医学研究理事会 (mMRC) 修改的呼吸障碍得分之间观察到正相关性.
- 疾病持续时间与BMI负相关,与需要协助积极相关;辅助设备的使用与年龄和mMRC相关.
- 一名患者在初始评估后1.5年发展出亚大规模肺栓塞.
结论:
- 建议在患有晚期疾病的老年PD患者密切监测DVT,特别是那些使用辅助设备或出现呼吸障碍增加的患者.
- 需要进一步的研究来调查DVT预防在高风险PD患者的益处.
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