关于模拟目标试验 (TARGET) 准则的观察性研究的TrAnsparent报告的开发
Harrison J Hansford1,2, Aidan G Cashin3,2, Matthew D Jones3,2
1School of Health Sciences, Faculty of Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia h.hansford@unsw.edu.au.
BMJ open
|September 12, 2023
概括
一项新的报告准则,即对模拟目标试验 (TARGET) 的观察性研究的透明报告,将提高观察性研究的质量. 这一准则将提高健康决策的可靠性,当随机试验是不可能的.
科学领域:
- 流行病学 流行病学
- 卫生研究方法论 卫生研究方法论
背景情况:
- 当随机试验不可行时,观察性研究对于健康决策至关重要.
- 目标试验方法最大限度地减少了观察性研究中估计干预效应的偏差.
- 对目标试验模拟的不完整报告阻碍了研究结果的评估和综合.
研究的目的:
- 描述开发观察性研究模拟目标试验 (TARGET) 报告准则的TrAnsparent报告的方法.
- 提高模拟目标试验的观察性研究的透明度和质量.
主要方法:
- 发表的目标试验模拟的系统审查.
- 通过在线调查进行专家咨询,以确定和完善指南项目.
- 共识会议以优先考虑和整合关键项目.
- 该指南和附带的解释文件的试点测试.
主要成果:
- 开发TARGET准则包括五个阶段,从系统审查到利益相关者传播.
- 该过程包括专家共识和试点测试,以确保实用性和相关性.
结论:
- 该TARGET报告准则旨在加强观察性研究的评估,综合和解释.
- 广泛传播和利益相关方的合作伙伴关系将最大限度地提高采用率并提高报告质量.
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