在移植患者中查脏细胞癌:单中心回顾性研究
Binoy Yohannan1, Arthi Sridhar2, Harmanpreet Kaur3
1Department of Hematology and Oncology, The University of Texas Health Sciences Center at Houston, Houston, Texas, USA binoyyohannan87@gmail.com.
BMJ open
|September 12, 2023
概括
在移植 (RT) 接受者中查脏细胞癌 (RCC) 显著改善了存活率. 通过查进行早期诊断导致早期疾病,并且RT患者没有与RCC相关的死亡.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 在瘤学瘤学.
- 移植手术 移植手术
背景情况:
- 接受移植 (RT) 的人患细胞癌 (RCC) 的风险增加.
- 在这个脆弱人群中,有效的RCC查方案对于早期检测和改善结果至关重要.
研究的目的:
- 评估细胞癌 (RCC) 查在移植 (RT) 接受者的有效性.
- 为了比较诊断时的RCC阶段和查和未查RT接受者之间的患者结果.
主要方法:
- 单中心回顾性研究,包括1998年移植接受者.
- 鉴定了20名移植后RCC患者,根据查状态 (超声波或CT) 对结果进行了比较.
主要成果:
- 接受查的RT后RCC患者 (n=12) 被诊断出患有早期疾病 (I/II阶段) 并实现治愈.
- 没有查的患者 (n=8) 患有较高的晚期RCC发病率 (第四阶段),所有患者都患有转移性疾病和死亡率.
- 在查和未查患者之间观察到RCC特异性生存率的统计学上显著差异 (p=0.01).
结论:
- 在移植患者中查脏细胞癌是有效的检测早期的疾病.
- 实施查协议可以显著降低RT接受者群体中与RCC相关的死亡率.
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