在日本使用怀孕出生登记数据的晚期早产单身婴儿中,与低出生体重相关的因素
Yoshifumi Kasuga1, Kunio Tanaka1, Keisuke Akita1
1Department of Obstetrics and Gynecology, Keio University School of Medicine, Shinjuku, Tokyo, Japan.
Journal of developmental origins of health and disease
|September 12, 2023
概括
超过一半的晚期早产 (LP) 婴儿出生时体重低 (LBW). 可改变的因素,如母亲体重不足和吸烟,与不可改变的因素一起,独立地增加了这些脆弱新生儿的LBW风险.
科学领域:
- 新生儿科学 新生儿科学
- 产科 产科 产科 产科 产科
- 公共卫生 公共卫生
背景情况:
- 晚期早产 (LP) 婴儿 (34 0/736 6/7周怀孕) 与低出生体重 (LBW) 婴儿 (<2500克) 具有共同的不良结果.
- 在LP出生和LBW之间的特定关联仍未得到充分探索.
- 了解LP婴儿的LBW风险因素对于有针对性的干预至关重要.
研究的目的:
- 为了确定晚期早产单胎新生儿中LBW的发病率.
- 在这个人群中确定与LBW相关的独立的孕产妇和产周风险因素.
主要方法:
- 对LP单子新生儿的日本注册数据 (2013年至2017年) 的回顾性分析.
- 不包括死胎和有不完整数据的婴儿.
- 后勤回归模型用于评估孕产妇/孕产后因素与LBW之间的关联.
主要成果:
- 在56160个LP单独分娩中,LBW是普遍存在的,影响了62.5% (n=35,113) 的LP单独分娩.
- 独立的LBW风险因素包括怀孕前体重不足,不充分的妊娠体重增加,吸烟,较年轻的孕妇年龄,无胎儿,高血压疾病,孕前,剖腹产和女性性别.
- 可修改和不可修改的因素都对LP新生儿的LBW风险作出了重大贡献.
结论:
- 在日本,超过一半的晚期早产婴儿出生时体重低.
- 识别和解决可修改的孕产妇风险因素是减少晚期早产婴儿LBW的关键.
- 需要考虑母亲和婴儿特征的多因素方法来管理晚期早产的LBW风险.
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