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[基于元分析的化合物对鱼类的生态毒性影响]

Hong Lu^1,2, Jin-Yang Zhou^1,2, Fan Yang^1,2

¹School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.

Huan jing ke xue= Huanjing kexue

|September 12, 2023

概括

和多醇基物质 (PFAS) 对鱼类构成重大风险,影响七个关键功能特征,其中形是最严重的. 水中毒性因鱼的性别和生命阶段而异,雌性胚胎是最脆弱的.

科学领域:

环境毒理学环境毒理学
水生生态毒理学水生生态毒理学
化学风险评估化学风险评估化学风险评估

背景情况:

和多醇基物质 (PFAS) 是持久性,生物积累性和有毒的有机污染物.
它们在水生生态系统中的广泛存在引起了人们对生态影响的担忧.
了解鱼类中的PFAS毒性对于环境管理至关重要.

研究的目的:

综合评估PFAS对鱼类各种功能特征的生物毒性影响.
分析鱼类的性别和发育阶段对PFAS毒性的影响.
为了确定特定的PFAS类型和与不良影响相关的暴露度.

主要方法:

进行了对64篇出版物的元分析.
使用效果大小来量化PFAS对鱼类功能特征的毒性.
分析了数据,以确定PFAS化学结构和暴露水平的影响.

主要成果:

在鱼类中研究的12个功能特征中,有7个被发现易受PFAS暴露的影响.
缺陷表现出最高的毒性反应 (lnRR=-2.5599),其次是发育,细胞损伤,繁殖,甲状腺反应,生长和生存.
在雌性鱼类中,PFAS毒性更高,并显著影响了胚胎发育.
硫酸盐组和长链PFAS显示出显著的毒性.
在中低度 (0.01-10毫克·L-1) 观察到急性毒性.

结论:

PFAS显著影响鱼类的多种功能特征,缺陷是主要关注的问题.
鱼的性别和发育阶段,特别是胚胎,是影响PFAS易感性的关键因素.
特定的PFAS化学结构和暴露度决定了毒理结果的严重程度.

关键词:

进行元分析分析.水生环境水生环境水生环境生态毒性生态毒性鱼类鱼类鱼类的鱼类鱼类.聚甲基物质 (PFAS) 是一种多基物质.

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