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Updated: Jul 16, 2025

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor LATS Biosensor
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布鲁斯的E2酶通过POSH介导的扩展降解来负面调节Hippo信号

Sha Song1,2,3, Xianjue Ma4,5,6

  • 1College of Life Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China.

Cell death & disease
|September 12, 2023
PubMed
概括

研究人员确定了Bruce,一个关键的E2酶,调节Hippo路径. 这一发现揭示了器官生长控制和瘤发生的新联系,揭示了无处不在信号的新联系.

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