儿童夏季腹:一个单心的法国流行病学观察研究
Camille Mallier1, Elisa Creuzet2, Céline Lambert3
1Service de Pédiatrie, CHU Clermont-Ferrand, 63000, Clermont-Ferrand, France.
Scientific reports
|September 12, 2023
概括
儿童夏季腹在法国很常见,超过80%的病例是传染性的. 肠病原性大肠杆菌,轮状病毒和沙门氏菌是最常见的原因,经常一起发生.
科学领域:
- 儿童传染病 儿童传染病
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 儿科腹是一个重大的全球公共卫生挑战.
- 虽然法国的冬季腹高峰记录得很好,但夏季腹的病因不明.
- 关于在法国夏季期间引起儿科腹的传染病原体的数据有限.
研究的目的:
- 确定法国夏季儿童感染性腹的患病率.
- 为了确定负责小儿夏季腹的特定病原体.
- 描述有助于这些腹发作的病因指导的常见因素.
主要方法:
- 在2019年6月至2019年9月和2020年期间,法国儿科急诊室进行了一项横截面的观察性研究.
- 多重胃肠道病原体面板被用于全面的病因学诊断.
- 采用多重对应分析,根据严重程度和病原体类型定义患者个人资料.
主要成果:
- 传染性夏季腹的患病率高达81.1%,包括95名儿童,主要是5岁以下的儿童.
- 总共确定了126种传染病原体,其中包括细菌 (50.0%),病毒 (38.1%) 和寄生虫 (11.9%).
- 关键的病原体包括肠病原性大肠杆菌 (18.9%),轮状病毒 (13.5%) 和沙门氏菌 (12.7%). 同时检测发生在51.9%的传染病例中.
结论:
- 传染病原体是法国夏季儿童腹的主要原因.
- 肠病原性大肠杆菌,轮状病毒和沙门氏菌是夏季儿童腹的重要原因.
- 了解病原体概况和共同检测可以为儿童夏季腹的病因诊断和管理策略提供信息.
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