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通过依赖m6A的DAPK3降解,YTHDF2促进胆囊癌的进展和耐吉他的抗性

Xuesong Bai1, Jiemin Chen2, Wenqin Zhang2

  • 1Department of General Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China.

Cancer science
|September 13, 2023
PubMed
概括

RNA结合蛋白YTHDF2通过降解瘤抑制剂DAPK3mRNA来促进胆囊癌 (GBC). 这种机制增强了GBC的进展和耐药性,提供了新的治疗点.

关键词:
在 DAPK3 中使用 DAPK3.这就是YTHDF2的原因.癌症的进展 癌症的进展胆囊癌是一种胆囊癌.m6A 修改的修改

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