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时间型和脂质代谢在北极逗留工人
Denis Gubin1,2,3, Alexander Vetoshkin3,4, Nina Shurkevich3
1Laboratory for Chronobiology and Chronomedicine, Research Institute of Biomedicine and Biomedical Technologies, Medical University, Tyumen, Russia.
Chronobiology international
|September 13, 2023
概括
与低度地区的居民相比,北极工人表现出更早的睡眠时间和更大的社交时差. 北极逗留工作经验与男性较差的脂质代谢和代谢健康指标有关.
科学领域:
- 时间生物学 时间生物学
- 职业健康 职业健康 职业健康
- 环境医学 环境医学
背景情况:
- 北极环境带来了独特的挑战,包括极端的光变化,可能会影响昼夜节律和睡眠模式.
- 了解在北极工作的人的睡眠特征和代谢健康对于评估职业健康风险至关重要.
- 以前的研究还没有广泛地比较北极逗留工人和低度地区居民之间的睡眠模式和代谢健康.
研究的目的:
- 为了比较北极临时工 (ASW) 和年龄相匹配的门居民 (TR) 的时间型,睡眠模式和睡眠质量.
- 调查北极停留工作经验 (ASWE),年龄和户外光照 (OLE) 与睡眠特征和代谢健康的关联.
- 检查ASW的睡眠质量指数和代谢健康代理之间的关系.
主要方法:
- 使用慕尼黑时刻型问卷 (MCTQ) 和匹兹堡睡眠质量指数 (PSQI) 来收集数据.
- 在ASW (n=180) 和TR (n=270) 之间,比较了睡眠参数,包括自由日的中期睡眠校正 (MSFsc) 和社会时差 (SJL).
- 分析了ASWE,年龄,OLE (工作和假日) 和代谢健康标志物 (脂质代谢,血压) 之间的相关性.
主要成果:
- 与TR相比,ASW表现出显著较早的MSFsc和较大的SJL,无论性别如何.
- 在男性中,ASWE,而不是年龄,与受损的脂质代谢 (更高的TG/HDL比率) 有显著的关联.
- 在ASW中较差的代谢健康代理与不利的PSQI组件有关;在空白天较高的OLE与较低的静缩和放缩血压相关.
结论:
- 北极逗留工人表现出不同的睡眠模式,其特点是早期睡眠时间和增加的社交时差,可能受到工作环境而不是光线暴露的影响.
- 北极逗留工作经验是与男性工人的不良代谢健康结果,特别是脂质代谢相关的重要因素.
- 睡眠的质量和数量是维持对北极工作条件暴露的人群代谢健康的关键考虑因素.
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