一个定制的人形3D打印幻影用于计算机断层扫描中的可重现性评估:瘤学案例研究
Carlo Cavaliere1, Dario Baldi1, Valentina Brancato1
1IRCCS Synlab SDN, Naples, Italy.
Frontiers in oncology
|September 13, 2023
概括
这项研究引入了用于计算机断层扫描 (CT) 研究的新型3D打印幻影,准确地复制了患者的胸部病变. 幻影可以在考虑辐射剂量的同时进行可重复的CT成像参数调查.
科学领域:
- 医疗成像医学成像
- 放射学 放射学是一门学科.
- 3D打印技术的使用
背景情况:
- 计算机断层扫描 (CT) 可重现性研究需要平衡辐射剂量与伦理考虑.
- 3D打印的幻影为CT特征和扫描仪进步的深入调查提供了一个有希望的途径.
研究的目的:
- 提出和验证一种新的人类形状的3D打印幻影用于胸部病变.
- 为了研究使用幻影的不同CT采集参数的体积和Hounsfield单位 (HU) 测量的变异性.
主要方法:
- 一个患有肺病变的患者的胸部CT扫描被根据HU范围划分为八个隔间.
- 从细分面具创建3D模型,并使用聚乳酸 (PLA) 化沉积建模 (FDM) 打印.
- 幻影扫描是在两个不同的CT扫描仪上以不同的管电压 (80,100,120kVp) 获得的,并分析了子相似系数 (DSC) 和平均HU.
主要成果:
- 在不同的设置和扫描仪中,在真实患者和幻影扫描之间观察到很好的重叠 (肺部DSC~0.9,病变~0.8).
- 幻影对肺部和病变口罩具有很高的相似性,表明这些结构的可靠表示.
- 虽然由于PLA材料,平均HU值无法直接与真实数据进行比较,但区间间强度值的比例保持不变.
结论:
- 这项研究验证了3D打印幻影在个性化CT研究中的可靠性.
- 这个工作流可以扩展到其他瘤成像研究,提高诊断准确性和扫描仪开发.
相关概念视频
Computed Tomography
4.6K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.6K
Imaging Studies III: Computed Tomography
26
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
26


