米诺环素诱导的眼睛色症
Carla Baaklini1, Natasha Kesav2, William Reinhart2
1Ophthalmology, University of Missouri, Columbia, USA.
Cureus
|September 13, 2023
概括
抗生素米诺环素可以引起眼球,这是一种罕见的疾病,导致皮膜,视网膜和皮肤的蓝灰色变色. 这种持续的色素可能会发生即使在停止服用药物后.
科学领域:
- 眼科医生 眼科 眼科
- 皮肤病学 皮肤病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 米诺环素是一种广泛使用的抗生素,具有已知的副作用.
- 补腺炎是一种慢性炎症性皮肤疾病.
- 眼睛色症是一种罕见的疾病,其特点是眼睛组织中颜色沉积.
研究的目的:
- 报告一种由米诺环素诱导的眼球色病例.
- 描述这种情况的膜,视网膜和皮肤表现.
- 讨论尽管药物戒断,但色素的长期持续性.
主要方法:
- 一个65岁的男性患者的病例报告.
- 详细的眼科评估,包括 fundus 检查和光学连贯性断层扫描 (OCT).
- 审查患者的药物 anamnesis,特别是长期使用米诺环素.
主要成果:
- 这位患者在经过四年米诺环素治疗后出现了双边,指甲床和牙变色.
- 眼科发现包括扩散的蓝色-灰色的膜过敏颜色和带有视网膜色素表皮质沉积物的胸膜的蓝色.
- 在停止使用米诺环林后,颜色持续了6年.
结论:
- 米诺环素可以诱导眼球偏光症,显著地影响膜和视网膜.
- 观察到的色素可能是持久和持久的,即使在病原体被移除后.
- 管理重点是患者的耐受性和监测.
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