相关实验视频

Updated: Jul 16, 2025

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells
09:16

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells

Published on: September 1, 2019

7.6K

在一个患有严重骨质疏松症的年轻男性中发现了一种新的RUNX1遗传变异

Tomasz J Block1,2, Cat Shore-Lorenti3, Roger Zebaze4

  • 1Department of Endocrinology Monash Health Melbourne Victoria Australia.

JBMR plus
|September 13, 2023
PubMed
概括

一个罕见的转录因子1 (RUNX1) 基因的罕见遗传变异在一个年轻人身上引起了严重的骨质疏松症和骨折. 这突出了RUNX1的亮点.

关键词:
合成代谢疗法 合成代谢疗法病性骨质疏松症是什么意思这是一种骨质遗传学.年轻成年人的骨质疏松症.一个RUNX1遗传变异.

更多相关视频

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

9.8K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila00:06

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

13.7K

相关概念视频

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.6K