用明显扩散系数对直肠癌淋巴结分期进行MRI评估
Ingrida Pikūnienė1, Žilvinas Saladžinskas2, Algidas Basevičius1
1Department of Radiology, Hospital of Lithuanian University of Health Sciences Kauno Klinikos, Kaunas, LTU.
Cureus
|September 13, 2023
概括
表面扩散系数 (ADC) MRI显示了直肠瘤和淋巴结的明显ADC值,有助于癌症分期. 治疗类型会影响淋巴结中的ADC值,影响诊断准确度.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 结肠直肠癌是全球领先的癌症诊断.
- 淋巴结转移显著影响患者的预后.
- 像扩散权重成像 (DWI) 等先进的MRI技术对于检测淋巴结转移至关重要.
研究的目的:
- 评估表面扩散系数 (ADC) MRI 在分期直肠癌淋巴结转移中的有效性.
- 为了比较瘤和淋巴结之间的ADC值.
- 评估不同治疗方式 (化疗与化疗放射治疗) 对ADC值的影响.
主要方法:
- 对89名II-III期直肠癌患者进行前性研究.
- 所有患者都接受了1.5TMRI,T2加权和DWI序列.
- 在瘤,淋巴结和直肠壁上定义了感兴趣的区域,以计算ADC值.
主要成果:
- 结直肠癌的ADC显示AUC为0.688 (截止值:0.99 x 10-3 mm2/s).
- 淋巴结ADC显示AUC为0.508 (截止点:0.9 x 10-3mm2/s). 淋巴结ADC显示AUC为0.508 (截止点:0.9 x 10-3mm2/s). 淋巴结ADC显示AUC为0.508 (截止点:0.9 x 10-3mm2/s). 淋巴结ADC显示AUC为0.508 (截止点:0.9 x 10-3mm2/s). 淋巴结ADC显示AUC为0.508 (截止点:0.9 x 10-3mm2/s).
- 瘤和淋巴结ADC值之间没有发现相关性. 治疗类型影响了 inguinal 淋巴结中的 ADC 差异.
结论:
- ADC-MRI可以区分直肠瘤和淋巴结.
- 淋巴结中的ADC值根据接受的治疗而有所不同.
- ADC-MRI显示了改善直肠癌中淋巴结分期的潜力.
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