对益生菌给药对与年龄相关的肉症影响的元分析
Nafiseh Shokri-Mashhadi1, Fatemeh Navab2, Shakila Ansari2
1Department of Clinical Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center Isfahan University of Medical Sciences Isfahan Iran.
Food science & nutrition
|September 13, 2023
概括
益生菌补充可以改善55岁以上成年人的肌肉质量和功能. 持续使用超过12周可显著增强肌肉力量,为与年龄相关的肌肉衰退提供了潜在的策略.
科学领域:
- 老年学是一门学科.
- 微生物学 微生物学
- 营养科学 营养科学
背景情况:
- 在全球范围内,与年龄相关的疾病,包括肉症,正在增加.
- 需要有效的肌肉健康干预措施.
- 关于益生菌对肉症的影响的证据有限.
研究的目的:
- 系统地审查和分析益生菌补充剂对肉类的成分的影响.
- 评估益生菌在改善老年人肌肉健康方面的疗效.
主要方法:
- 来自PubMed,SCOPUS,Web of Science和Cochrane图书馆的干预研究的元分析.
- 包括到2022年10月之前调查益生菌对萨尔科佩尼亚成分的影响的研究.
- 偏差风险的Cochrane质量评估工具;效果大小的随机效应模型.
主要成果:
- 益生菌补充剂显著改善了肌肉质量 (WMD:0.55公斤) 和肌肉功能 (WMD:0.13).
- 超过12周的补充显着增强了肌肉力量 (WMD: 1.16).
- 没有观察到对体重指数或其他人类指数的显著影响.
结论:
- 益生菌对55岁以上的成年人肌肉质量和功能产生有益影响.
- 长时间使用益生菌 (12周以上) 与肌肉强度的提高有关.
- 益生菌补充剂可能是一个可行的策略来对抗肉症.
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