长期的同性恋与全球人口样本中的婚姻偏好相关
Samali Anova Sahoo1, Rslan A Zaidi1, Santosh Anagol2
1Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
亲属关系,父母共同的近年祖先,增加长期运行在孩子的同卵性 (ROH). 这种遗传模式与表妹婚姻偏好有关,影响了人类遗传变异研究.
科学领域:
- 人类遗传学 人类遗传学
- 人口遗传学 人口遗传学
- 人类学是人类学.
背景情况:
- 血缘关系的结合导致长期的同胞性 (ROH) 由于共同的父母祖先.
- 增加的ROH负担与血缘关系人口的衰退性疾病有关.
- 血缘关系对遗传变异模式的全球影响仍未得到充分研究.
研究的目的:
- 调查血缘关系与遗传变异模式之间的全球关联.
- 确定婚姻习惯是否影响长期同卵性性 (ROH) 的分布.
主要方法:
- 汇编了来自全球395个人口的已发表的遗传数据.
- 收集有关婚姻惯例和血缘关系率的信息.
- 分析了报告的表妹婚姻偏好与ROH分布之间的关系.
主要成果:
- 报告的表妹婚姻偏好显示出与ROH分布有可检测的关联.
- 血缘关系使ROH长于10厘米的预期数量增加了2.2的系数.
- 婚姻习惯解释了ROH分布变化的很小一部分.
结论:
- 血缘关系和婚姻实践是人类人口历史中的重要因素,用于基因变异建模.
- 人口遗传数据只提供了对文化婚姻偏好的部分见解.
- 需要进一步的研究才能充分理解文化与遗传之间的相互作用.
更多相关视频
13:55Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
Published on: February 3, 2013
10:08Genetic Mapping of Thermotolerance Differences Between Species of Saccharomyces Yeast via Genome-Wide Reciprocal Hemizygosity Analysis
Published on: August 12, 2019
相关概念视频
Hardy-Weinberg Principle
Longitudinal Studies
Testing a Claim about Population Proportion
There are two methods of testing a claim about a population proportion: (1) Using the sample proportion from the data where a binomial distribution is approximated to the normal distribution and (2) Using the binomial probabilities calculated from the data.
The first method uses normal distribution as an approximation to the binomial distribution. The requirements are as follows: sample size is large...
Natural Selection and Mating Preferences
Females, due to their biological roles in conception, pregnancy, and nursing,...
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Longitudinal Research
