儿童早期常见的与完全头皮脱发相关的疾病:一篇综述
Michaela Rose Rand1, Katerina Yale1, Brian Satoshi Kato2
1Department of Dermatology, University of California, Irvine, California 92697, USA.
International journal of trichology
|September 13, 2023
概括
本综述确定了六种常见的遗传疾病,导致儿童头皮毛发完全脱落. 早期识别这些遗传性脱毛原因可以改善患儿的诊断和预后.
科学领域:
- 儿科皮肤病学 儿科皮肤病学
- 医学遗传学 医学遗传学
- 三学是指三学的学科.
背景情况:
- 儿童头皮毛发完全脱落,或白发症,造成显著的痛苦.
- 虽然感染和创伤是常见的原因,但遗传因素在儿科脱发症中起着至关重要的作用.
- 识别遗传倾向是准确诊断和管理的关键.
研究的目的:
- 确定和审查与婴儿和儿童头皮完全脱发相关的常见遗传疾病.
- 综合当前关于儿科人口遗传性脱毛的文献.
- 提高临床医生对儿科脱发遗传原因的认识.
主要方法:
- 从1962年到2019年,PubMed数据库的综合文献审查.
- 包括至少有5例人类遗传性脱毛病例报告的研究.
- 专注于临床试验,回顾性研究和英语案例报告.
主要成果:
- 六种遗传条件被确定为儿童头皮毛发完全脱落的常见原因.
- 这些包括总体脱发症/普遍脱发症 (AU),带有乳头病变的心脏病,先天性AU,遗传性维生素D抗性IIA型老皮病,精神迟缓的脱发症以及纯毛和指甲外皮性质疏松症.
- 该综述强调了儿童脱发背后的多样化遗传环境.
结论:
- 多种遗传和环境因素会导致儿童头皮毛发完全脱落.
- 提高对这些遗传疾病的临床意识对于及时诊断至关重要.
- 改进的诊断能力可以导致遗传性脱发症儿童的预后更好.
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